Which API calls and RPC modules are supported?

Check out the QuickNode Docs: https://www.quicknode.com/docs

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QuickNode API: web3, eth, net, parity, trace (add-on).

OpenEthereum Dedicated: web3, eth, net, parity, trace (included).

Geth Dedicated: web3, eth, net, shh, txpool, debug.

Bitcoin Dedicated: Bitcoin Core RPC API on bitcoind, including "txindex".